Protein sequence for HAGRID 40 (EGFR) for HAGRID 40 (EGFR)


Gene information

HGNC symbolEGFR
Common nameepidermal growth factor receptor

GO protein functions

GO:0001948glycoprotein binding
GO:0003682chromatin binding
GO:0003690double-stranded DNA binding
GO:0004709MAP kinase kinase kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0004716signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0004888transmembrane signaling receptor activity
GO:0005006epidermal growth factor-activated receptor activity
GO:0005006epidermal growth factor-activated receptor activity
GO:0005006epidermal growth factor-activated receptor activity
GO:0005088Ras guanyl-nucleotide exchange factor activity
GO:0005178integrin binding
GO:0005515protein binding
GO:0005516calmodulin binding
GO:0005524ATP binding
GO:0019899enzyme binding
GO:0019901protein kinase binding
GO:0019903protein phosphatase binding
GO:0030235nitric-oxide synthase regulator activity
GO:0031625ubiquitin protein ligase binding
GO:0042802identical protein binding
GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046982protein heterodimerization activity
GO:0048408epidermal growth factor binding
GO:0051015actin filament binding
GO:0098641cadherin binding involved in cell-cell adhesion

Protein sequence for HAGRID 40 (EGFR)

Protein sequence for HAGRID 40 (EGFR) source (RefSeq)NP_005219
Sequence length1210 aa

Sequence

     1  MRPSGTAGAA LLALLAALCP ASRALEEKKV CQGTSNKLTQ LGTFEDHFLS LQRMFNNCEV
    61  VLGNLEITYV QRNYDLSFLK TIQEVAGYVL IALNTVERIP LENLQIIRGN MYYENSYALA
   121  VLSNYDANKT GLKELPMRNL QEILHGAVRF SNNPALCNVE SIQWRDIVSS DFLSNMSMDF
   181  QNHLGSCQKC DPSCPNGSCW GAGEENCQKL TKIICAQQCS GRCRGKSPSD CCHNQCAAGC
   241  TGPRESDCLV CRKFRDEATC KDTCPPLMLY NPTTYQMDVN PEGKYSFGAT CVKKCPRNYV
   301  VTDHGSCVRA CGADSYEMEE DGVRKCKKCE GPCRKVCNGI GIGEFKDSLS INATNIKHFK
   361  NCTSISGDLH ILPVAFRGDS FTHTPPLDPQ ELDILKTVKE ITGFLLIQAW PENRTDLHAF
   421  ENLEIIRGRT KQHGQFSLAV VSLNITSLGL RSLKEISDGD VIISGNKNLC YANTINWKKL
   481  FGTSGQKTKI ISNRGENSCK ATGQVCHALC SPEGCWGPEP RDCVSCRNVS RGRECVDKCN
   541  LLEGEPREFV ENSECIQCHP ECLPQAMNIT CTGRGPDNCI QCAHYIDGPH CVKTCPAGVM
   601  GENNTLVWKY ADAGHVCHLC HPNCTYGCTG PGLEGCPTNG PKIPSIATGM VGALLLLLVV
   661  ALGIGLFMRR RHIVRKRTLR RLLQERELVE PLTPSGEAPN QALLRILKET EFKKIKVLGS
   721  GAFGTVYKGL WIPEGEKVKI PVAIKELREA TSPKANKEIL DEAYVMASVD NPHVCRLLGI
   781  CLTSTVQLIT QLMPFGCLLD YVREHKDNIG SQYLLNWCVQ IAKGMNYLED RRLVHRDLAA
   841  RNVLVKTPQH VKITDFGLAK LLGAEEKEYH AEGGKVPIKW MALESILHRI YTHQSDVWSY
   901  GVTVWELMTF GSKPYDGIPA SEISSILEKG ERLPQPPICT IDVYMIMVKC WMIDADSRPK
   961  FRELIIEFSK MARDPQRYLV IQGDERMHLP SPTDSNFYRA LMDEEDMDDV VDADEYLIPQ
  1021  QGFFSSPSTS RTPLLSSLSA TSNNSTVACI DRNGLQSCPI KEDSFLQRYS SDPTGALTED
  1081  SIDDTFLPVP EYINQSVPKR PAGSVQNPVY HNQPLNPAPS RDPHYQDPHS TAVGNPEYLN
  1141  TVQPTCVNST FDSPAHWAQK GSHQISLDNP DYQQDFFPKE AKPNGIFKGS TAENAEYLRV
  1201  APQSSEFIGA     
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