Protein sequence for HAGRID 41 (ERBB2) for HAGRID 41 (ERBB2)

Gene information

HGNC symbolERBB2
Common nameerb-b2 receptor tyrosine kinase 2

GO protein functions

GO:0001042RNA polymerase I core binding
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004713protein tyrosine kinase activity
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0004716signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0004888transmembrane signaling receptor activity
GO:0005088Ras guanyl-nucleotide exchange factor activity
GO:0005515protein binding
GO:0005524ATP binding
GO:0008022protein C-terminus binding
GO:0019838growth factor binding
GO:0019903protein phosphatase binding
GO:0042802identical protein binding
GO:0043125ErbB-3 class receptor binding
GO:0046934phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0046982protein heterodimerization activity
GO:0046982protein heterodimerization activity
GO:0046983protein dimerization activity

Protein sequence for HAGRID 41 (ERBB2)

Protein sequence for HAGRID 41 (ERBB2) source (RefSeq)NP_004439
Sequence length1255 aa

Sequence

     1  MELAALCRWG LLLALLPPGA ASTQVCTGTD MKLRLPASPE THLDMLRHLY QGCQVVQGNL
    61  ELTYLPTNAS LSFLQDIQEV QGYVLIAHNQ VRQVPLQRLR IVRGTQLFED NYALAVLDNG
   121  DPLNNTTPVT GASPGGLREL QLRSLTEILK GGVLIQRNPQ LCYQDTILWK DIFHKNNQLA
   181  LTLIDTNRSR ACHPCSPMCK GSRCWGESSE DCQSLTRTVC AGGCARCKGP LPTDCCHEQC
   241  AAGCTGPKHS DCLACLHFNH SGICELHCPA LVTYNTDTFE SMPNPEGRYT FGASCVTACP
   301  YNYLSTDVGS CTLVCPLHNQ EVTAEDGTQR CEKCSKPCAR VCYGLGMEHL REVRAVTSAN
   361  IQEFAGCKKI FGSLAFLPES FDGDPASNTA PLQPEQLQVF ETLEEITGYL YISAWPDSLP
   421  DLSVFQNLQV IRGRILHNGA YSLTLQGLGI SWLGLRSLRE LGSGLALIHH NTHLCFVHTV
   481  PWDQLFRNPH QALLHTANRP EDECVGEGLA CHQLCARGHC WGPGPTQCVN CSQFLRGQEC
   541  VEECRVLQGL PREYVNARHC LPCHPECQPQ NGSVTCFGPE ADQCVACAHY KDPPFCVARC
   601  PSGVKPDLSY MPIWKFPDEE GACQPCPINC THSCVDLDDK GCPAEQRASP LTSIVSAVVG
   661  ILLVVVLGVV FGILIKRRQQ KIRKYTMRRL LQETELVEPL TPSGAMPNQA QMRILKETEL
   721  RKVKVLGSGA FGTVYKGIWI PDGENVKIPV AIKVLRENTS PKANKEILDE AYVMAGVGSP
   781  YVSRLLGICL TSTVQLVTQL MPYGCLLDHV RENRGRLGSQ DLLNWCMQIA KGMSYLEDVR
   841  LVHRDLAARN VLVKSPNHVK ITDFGLARLL DIDETEYHAD GGKVPIKWMA LESILRRRFT
   901  HQSDVWSYGV TVWELMTFGA KPYDGIPARE IPDLLEKGER LPQPPICTID VYMIMVKCWM
   961  IDSECRPRFR ELVSEFSRMA RDPQRFVVIQ NEDLGPASPL DSTFYRSLLE DDDMGDLVDA
  1021  EEYLVPQQGF FCPDPAPGAG GMVHHRHRSS STRSGGGDLT LGLEPSEEEA PRSPLAPSEG
  1081  AGSDVFDGDL GMGAAKGLQS LPTHDPSPLQ RYSEDPTVPL PSETDGYVAP LTCSPQPEYV
  1141  NQPDVRPQPP SPREGPLPAA RPAGATLERA KTLSPGKNGV VKDVFAFGGA VENPEYLTPQ
  1201  GGAAPQPHPP PAFSPAFDNL YYWDQDPPER GAPPSTFKGT PTAENPEYLG LDVPV
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