Human Ageing-Associated Genes

HAGRID HGNC symbol Common name Display entry Source
39MYCv-myc avian myelocytomatosis viral oncogene homologMYCcell,upstream
47PDGFBplatelet-derived growth factor beta polypeptidePDGFBupstream
48EGFepidermal growth factorEGFupstream
53SSTsomatostatinSSTupstream
62PIN1peptidylprolyl cis/trans isomerase, NIMA-interacting 1PIN1upstream
64CREBBPCREB binding proteinCREBBPupstream
67RPA1replication protein A1, 70kDaRPA1upstream
70S100BS100 calcium binding protein BS100Bupstream,putative
73IGFBP3insulin-like growth factor binding protein 3IGFBP3upstream
76EGR1early growth response 1EGR1upstream
85UBE2Iubiquitin-conjugating enzyme E2IUBE2Iupstream
93STK11serine/threonine kinase 11STK11upstream
94EP300E1A binding protein p300EP300upstream
110ARandrogen receptorARupstream
170SP1Sp1 transcription factorSP1upstream
172JUNjun proto-oncogeneJUNupstream
184HESX1HESX homeobox 1HESX1upstream
190TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)TFAP2Aupstream
192CREB1cAMP responsive element binding protein 1CREB1upstream,putative
194TBPTATA box binding proteinTBPupstream
207HDAC2histone deacetylase 2HDAC2functional,upstream
210MDM2MDM2 proto-oncogene, E3 ubiquitin protein ligaseMDM2upstream
211SUMO1small ubiquitin-like modifier 1SUMO1upstream
140SNCGsynuclein, gamma (breast cancer-specific protein 1)SNCGupstream
216ESR1estrogen receptor 1ESR1upstream
222GHRHRgrowth hormone releasing hormone receptorGHRHRupstream,putative
233ZMPSTE24zinc metallopeptidase STE24ZMPSTE24upstream,putative
253HIC1hypermethylated in cancer 1HIC1upstream
256PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alphaPPARGC1Amammal,upstream,downstream
271SOCS2suppressor of cytokine signaling 2SOCS2functional,upstream
277SUN1Sad1 and UNC84 domain containing 1SUN1upstream
283NFE2L2nuclear factor, erythroid 2-like 2NFE2L2cell,upstream
286PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alphaPIK3CAupstream
287C1QAcomplement component 1, q subcomponent, A chainC1QAupstream
301SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1SERPINE1upstream