Human Ageing-Associated Genes

HAGRID	HGNC symbol	Common name	Display entry	Source
19	PTPN11	protein tyrosine phosphatase, non-receptor type 11	PTPN11	downstream
21	STAT5B	signal transducer and activator of transcription 5B	STAT5B	downstream
22	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	STAT3	downstream
23	STAT5A	signal transducer and activator of transcription 5A	STAT5A	downstream
26	GH1	growth hormone 1	GH1	mammal,functional,downstream
33	PTPN1	protein tyrosine phosphatase, non-receptor type 1	PTPN1	downstream
36	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	PIK3CB	model,downstream
37	NGFR	nerve growth factor receptor	NGFR	downstream
40	EGFR	epidermal growth factor receptor	EGFR	downstream
41	ERBB2	erb-b2 receptor tyrosine kinase 2	ERBB2	downstream
49	IL2RG	interleukin 2 receptor, gamma	IL2RG	downstream
51	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	PDGFRB	downstream
52	EPOR	Erythropoietin receptor	EPOR	downstream
54	PRKCD	protein kinase C, delta	PRKCD	downstream
56	RET	ret proto-oncogene	RET	downstream
57	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	PLCG2	downstream
65	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	HIF1A	functional,downstream
43	NCOR1	nuclear receptor corepressor 1	NCOR1	downstream
78	ABL1	ABL proto-oncogene 1, non-receptor tyrosine kinase	ABL1	functional,downstream
96	PML	promyelocytic leukemia	PML	cell,downstream
97	GSK3B	glycogen synthase kinase 3 beta	GSK3B	downstream
99	PRKCA	protein kinase C, alpha	PRKCA	downstream
100	SSTR3	somatostatin receptor 3	SSTR3	downstream
111	GTF2H2	general transcription factor IIH, polypeptide 2, 44kDa	GTF2H2	downstream
114	FEN1	flap structure-specific endonuclease 1	FEN1	downstream
118	POLD1	polymerase (DNA directed), delta 1, catalytic subunit	POLD1	downstream
119	BAX	BCL2-associated X protein	BAX	downstream,putative
122	GRB2	growth factor receptor-bound protein 2	GRB2	downstream
134	LRP2	low density lipoprotein receptor-related protein 2	LRP2	downstream
164	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	YWHAZ	downstream
165	PTK2B	protein tyrosine kinase 2 beta	PTK2B	downstream
166	PTK2	protein tyrosine kinase 2	PTK2	downstream
171	FLT1	fms-related tyrosine kinase 1	FLT1	downstream
175	MAPK3	mitogen-activated protein kinase 3	MAPK3	downstream
176	HMGB1	high mobility group box 1	HMGB1	downstream
177	CCNA2	cyclin A2	CCNA2	downstream
178	HMGB2	high mobility group box 2	HMGB2	downstream
179	MAP3K5	mitogen-activated protein kinase kinase kinase 5	MAP3K5	downstream
185	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	PIK3R1	downstream
193	ATF2	activating transcription factor 2	ATF2	downstream
196	HBP1	HMG-box transcription factor 1	HBP1	downstream
215	JAK2	Janus kinase 2	JAK2	downstream
201	CDK1	cyclin-dependent kinase 1	CDK1	downstream
202	TFDP1	transcription factor Dp-1	TFDP1	cell,downstream
18	E2F1	E2F transcription factor 1	E2F1	cell,downstream
180	TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	TAF1	downstream
71	VCP	valosin containing protein	VCP	downstream
75	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	NR3C1	downstream
223	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	CTNNB1	downstream
87	PDPK1	3-phosphoinositide dependent protein kinase 1	PDPK1	downstream
246	PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	PPM1D	downstream,putative
250	CDC42	cell division cycle 42	CDC42	cell,downstream
252	CLOCK	clock circadian regulator	CLOCK	functional,downstream
256	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	PPARGC1A	mammal,upstream,downstream
259	FGF23	fibroblast growth factor 23	FGF23	downstream,putative
285	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	PDGFRA	downstream